This medication can dry up and thicken mucus in your lungs, which makes it tougher to breathe and distinct your lungs. To help you prevent this impact, consume lots of fluids Unless of course usually directed by your physician.
Steer clear of the use of promethazine HCl and codeine phosphate oral solution in adolescents 12 to eighteen many years of age who have other chance components which could increase their sensitivity on the respiratory depressant consequences of codeine unless the advantages outweigh the pitfalls.
Promethazine/Codeine is really a prescription medication applied to take care of cough and higher respiratory tract indications connected with allergies or typical cold.
Accidental Ingestion: Accidental ingestion of even 1 dose, Primarily by youngsters, can result in a fatal overdose of codeine.
If you must consider it for years Your system could become accustomed to it (often known as tolerance). Meaning you may need bigger doses to regulate your ache as time passes.
Problems It is Secure to choose an each day painkiller which include paracetamol or ibuprofen. Speak with your medical doctor In the event the head aches worsen or final for a longer time than a week.
Because of the likely for promethazine to reverse epinephrine’s vasopressor outcome, epinephrine should NOT be applied to take care of click here hypotension related with promethazine overdose.
No proof of tumorigenicity was observed in male and woman mice at codeine dietary doses approximately 400 mg/kg/day (somewhere around akin to 45 periods the MRHD on the mg/m2 foundation).
Speak to nearby point out Skilled licensing board or state controlled substances authority for information on how to forestall and detect abuse or diversion of this product or service.
Anaphylaxis: Anaphylaxis continues to be documented with codeine, one of many substances in promethazine HCl and codeine phosphate oral Resolution.
5.19 Neonatal Opioid Withdrawal Syndrome Promethazine HCl and codeine phosphate oral Alternative will not be encouraged to be used in Expecting Girls. Prolonged use of promethazine HCl and codeine phosphate oral Alternative during pregnancy may result in withdrawal during the neonate. Neonatal opioid withdrawal syndrome, compared with opioid withdrawal syndrome in Grown ups, can be lifetime-threatening if not recognized and treated, and necessitates administration In accordance with protocols created by neonatology experts.
Breastfeeding isn't suggested while having this drug; nursing moms needs to be instructed to seek speedy clinical awareness for infants enduring improved sleepiness, difficulty breastfeeding, respiratory problems, or limpness.
While in the mid 1800s, cocaine was first isolated from coca leaves and by 1880, it absolutely was being extensively employed for medicinal applications. The drug ongoing to get attractiveness, but with it arrived some perilous Unwanted side effects and repercussions. In 1922, cocaine was officially banned, making it unlawful to employ during the U.S.
Due to the threats of habit, abuse, and misuse with opioids, even at proposed doses [see Warnings and Precautions (five.one)], reserve promethazine HCl and codeine phosphate oral Resolution to be used in adult individuals for whom the advantages of cough suppression are expected to outweigh the pitfalls, As well as in whom an suitable assessment from the etiology on the cough has long been produced.